Major Questions about Teres Minor: The Pattern of Reactive Changes in a Precolumbian Human Skeletal Sample From Illinois

The ubiquitous presence of reactive changes at the insertion of a minor muscle of the rotator cuff on the proximal humerus (teres minor) is analyzed in an adult Late Woodland (AD 800–1150) period osteological sample (N = 43) from west-central Illinois (Schroeder Mounds, 11HE177). Fifty-seven percent left (20/35) and sixty-nine percent right humeri (25/36) have reactive change to the t. minor facet. There are no statistically significant differences by sex or side asymmetry. Reactive change generally co-associates with greater humeral robusticity. Besides a minor collaborative role in shoulder joint stability, teres minor has a limit range of movement as an abductor and external rotator of the arm. Injuries to the t. minor are exrememly rare in modern clinical contexts and only in athletes who engage in actvivites that utilize overhead arm movements. That is, the reactive change may be associated with particular arm movements or body posture which, in this pre-Columbian horticulturalist sample, may be related to activities for which there are no modern clinical correlates

Low-Density Granulocytes Are a Novel Immunopathological Feature in Both Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

Objective: To investigate whether low-density granulocytes (LDGs) are an immunophenotypic feature of patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD). Methods: Blood samples were collected from 20 patients with NMOSD and 17 patients with MS, as well as from 15 patients with Systemic Lupus Erythematosus (SLE) and 23 Healthy Donors (HD). We isolated peripheral blood mononuclear cells (PBMCs) with density gradient separation and stained the cells with antibodies against CD14, CD15, CD16, and CD45, and analyzed the cells by flow cytometry or imaging flow cytometry. We defined LDGs as CD14-CD15(high) and calculated their share in total PBMC leukocytes (CD45+) as well as the share of CD16(hi) LDGs. Clinical data on disease course, medication, and antibody status were obtained. Results: LDGs were significantly more common in MS and NMOSD than in HDs, comparable to SLE samples (median values HD 0.2%, MS 0.9%, NMOSD 2.1%, SLE 4.3%). 0/23 of the HDs, but 17/20 NMOSD and 11/17 MS samples as well as 13/15 SLE samples had at least 0.7 % LDGs. NMOSD patients without continuous immunosuppressive treatment had significantly more LDGs compared to their treated counterparts. LDG nuclear morphology ranged from segmented to rounded, suggesting a heterogeneity within the group. Conclusion: LDGs are a feature of the immunophenotype in some patients with MS and NMOSD

The interrelation between the electronic parameters of nitrogen atom and intramolecular interactions in ammonia derivatives

The electronic parameters and intramolecular interactions in the ground and transition states of inversion of the amines H₂NXHn (XHn=CH₃, NH₂, OH, F, SiH₃, PH₂, SH, Cl) were calculated using DFT (PBE96/def2-tzvpp) method. It was established that the electronacceptor properties of the XHn substituents has a prevailing influence on the change of the electronic parameters of nitrogen atom. Its increase leads to both a decrease of the charge on the nitrogen atom and an increase of the s-character and population of nitrogen lone pair (LP). All parameters under consideration correlate with the χ- and σᵢ-constants of the XHn substituents. The correlation coefficients increase when amines that contain X atoms only from one period are considered separately. It was found that the ρ values for amines containing X atoms from the second or third period are substantially different. The changes of the donor-acceptor interaction energies, s-character and LP population cannot be probable causes for different sensitivity of the electronic parameters of amines containing X atoms from different periods to the change of electron-acceptor properties of the XHn substituents. It was established that the mentioned parameters has only a subordinated influence in comparison with the influence of electron-acceptor ability of the XHn substituents. The negative charge on the nitrogen atom decreases with the increase of s-character and LP population and also with the decrease of energies of donor-acceptor interactions which lead to the withdrawal of electron density from the nitrogen atom. The s-character and LP population increase with the decrease of energies of donor-acceptor interactions which result in the reduction of electron density on the nitrogen atom. The total positive charges of the XHn groups and hydrogen atoms at the nitrogen atom decrease with increasing the electron-acceptor ability of the XHn substituents. The representation of the electron-acceptor properties of the substituents was shown to be more valid by using the χ-constants than by using the σᵢ-constants. The chlorine atom is a weak electron acceptor in comparison with an amino group

Spontaneous Symmetry Breaking in Twisted Noncommutative Quantum Theories

We analyse aspects of symmetry breaking for Moyal spacetimes within a quantisation scheme which preserves the twisted Poincar\'e symmetry. Towards this purpose, we develop the LSZ approach for Moyal spacetimes. The latter gives a formula for scattering amplitudes on these spacetimes which can be obtained from the corresponding ones on the commutative spacetime. This formula applies in the presence of spontaneous breakdown of symmetries as well.We also derive Goldstone's theorem on Moyal spacetime. The formalism developed here can be directly applied to the twisted standard model.Comment: +13 pages; minor changes in references,To appear in Phys Rev

Lehmann-Symanzik-Zimmermann S-Matrix elements on the Moyal Plane

Field theories on the Groenewold-Moyal(GM) plane are studied using the Lehmann-Symanzik-Zimmermann(LSZ) formalism. The example of real scalar fields is treated in detail. The S-matrix elements in this non-perturbative approach are shown to be equal to the interaction representation S-matrix elements. This is a new non-trivial result: in both cases, the S-operator is independent of the noncommutative deformation parameter $\theta_{\mu\nu}$ and the change in scattering amplitudes due to noncommutativity is just a time delay. This result is verified in two different ways. But the off-shell Green's functions do depend on $\theta_{\mu\nu}$. In the course of this analysis, unitarity of the non-perturbative S-matrix is proved as well.Comment: 18 pages, minor corrections, To appear in Phys. Rev. D, 201